ICTUImperial Clinical Trials Unit

Welcome to Imperial Clinical Trials Unit (ICTU)

This website is intended for people who are considering taking part in clinical trials and would like to find out more about what’s involved, why clinical trials are important and what the benefits of taking part in trials are. You can also find out about current clinical trials going on in ICTU and how to get involved.

Clinical Trials Search


CurrentAll Trials


Trial Details

Nucleos(t)ide withdrawal in HBeAg negative hepatitis B virus infection to promote HBsAg clearance

Design and Objective

Multicentre, randomised, open label trial comparing two management strategies to promote HBsAg loss in patients with HBeAg negative chronic HBV infection. To explore whether finite treatment with nucleos(t)ide analogues is feasible in patients with HBeAg (Hepatitis B ‘e’ antigen) negative chronic HBV (Hepatitis B Virus) infection.

Key inclusion criteria

• Age ≥ 18 • Chronic HBV infection • HBeAg negative • Nucleos(t)ide analogues treatment for ≥3 years • HBV DNA < 400 IU/ml ≥2 years • Informed consent

Study Disclaimer Statement