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HARMONY

Trial Details

  • Trial statusAnalysis
  • Study email contactHARMONY@imperial.ac.uk
  • Chief InvestigatorProfessor Neil Poulter
  • Project managerMary Cross
  • SponsorImperial College London
  • ISRCTN numbern/a
  • PhaseIV

Hellenic-Anglo Research into Morning Or Night antihypertensive drug deliverY Trial

Design and Objective

The objective is to detect a 3 mmHg difference in achieved mean 24 hour systolic BP, when antihypertensive medications are taken in the evening compared with intake of same medications in the morning.

Key inclusion criteria

- Aged 18-80 years - History of hypertension for at least 1 year - At least 3 months of constant antihypertensive medication (consisting of ≥ 1 antihypertensive drugs, each administered in one dose daily) - Relatively well controlled BP (150/90 mmHg and ≥ 115/65 mmHg on usual medication) at randomisation and prior 3 months

Study Disclaimer Statement