ICTUImperial Clinical Trials Unit

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This website is intended for people who are considering taking part in clinical trials and would like to find out more about what’s involved, why clinical trials are important and what the benefits of taking part in trials are. You can also find out about current clinical trials going on in ICTU and how to get involved.

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Trial Details

A randomised, prospective study, assessing changes in cerebral function in treatment naive HIV-1 infected subjects commencing either boosted atazanavir with Truvada or boosted darunavir with maraviroc

Design and Objective

When commencing antiretroviral therapy for the first time, improvements in brain function are frequently observed. However, whether these improvements may differ between different anti-HIV therapies is largely unknown. The purpose of this study is to compare two different combination anti-HIV therapies over 48 weeks and to assess if differences in improvement in brain function are observed over this period.

Key inclusion criteria

HIV-1 infected males or females, aged 18 years or above, with no previous antiretroviral treatment since HIV diagnosis.

Study Disclaimer Statement